Research Article

High-Throughput Untargeted Serum Metabolomics Analysis of Hyperuricemia Patients by UPLC-Q-TOF/MS

Table 1

Basic characteristics and biochemistry results of participants in the control group and HUA group.

ParametersControl group (n = 20)HUA group (n = 20)

Age (years)41.1 ± 12.640.3 ± 11.6
Men (%)55%55%
FSG (mmol/L)4.9 ± 0.45.8 ± 0.6
UA (µmol/L)320.4 ± 40.3481.6 ± 51.0
TG (mmol/L)1.52 ± 0.53.3 ± 1.2
ALT (U/L)23.6 ± 10.340.7 ± 15.9
AST (U/L)20.5 ± 5.727.7 ± 12.8
HDL (mmol/L)1.5 ± 0.41.2 ± 0.2
LDL (mmol/L)2.7 ± 0.63.6 ± 0.8
CR (µmol/L)79.5 ± 8.783.2 ± 14.7

Note. Continuous variables described as mean (standard deviation) and categorical variables as count (proportion). FSG: fasting serum glucose; UA: uric acid; TG: triglycerides; ALT: alanine aminotransferase; AST: aspartic aminotransferase; HDL: high-density lipoprotein cholesterol; LDL: low-density lipoprotein cholesterol; CR: creatinine. Significant difference from control at  < 0.05. Significant difference from control at p < 0.01.