Lower Somatic Mutation Levels in the λ Light-Chain Repertoires with Chronic HBV Infection

Figure 1

The diversity of κ (IgK) and λ (IgL) light-chain repertoires of the healthy human (HH) and inactive HBV carriers (IHB). (a) The diversity of unique clones in the IgK and IgL repertoires from the HH and IHB library. (b) The Margalef index was calculated to describe the repertoire diversity that was calculated, respectively, when 10, 100, 1000, 10000, 100000, and 1000000 sequences were randomly selected using the randomized table generated by R program. (c) The diversity of VJ gene rearrangements in the IgK and IgL repertoires from the HH and IHB library. (d) The diversity of unique CDR3 sequences in the IgK and IgL repertoires from the HH and IHB library.

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