Essential Oils Derived from Momordica charantia Seeds Exhibited Antiulcer Activity against Hydrogen Chloride/Ethanol and Indomethacin

Figure 4

Microscopic evaluation of the gastric mucosa in rats induced by indomethacin. (a) Rats pretreated with distilled water only. (b) Rats with indomethacin and distilled water. (c) Rats with indomethacin and ranitidine. (d) Rats with indomethacin and 10 mg/kg of MCEO. (e) Rats with indomethacin and 50 mg/kg of MCEO. (f) Rats with indomethacin and 100 mg/kg of MCEO. The sections were cut parallel to the muscle layer. Red arrow indicates epithelial disruption; black arrow indicates oedema; and blue arrow indicates the erosion extending to the muscularised mucosae. H&E staining, 100x magnification.

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