Essential Oils Derived from Momordica charantia Seeds Exhibited Antiulcer Activity against Hydrogen Chloride/Ethanol and Indomethacin

Table 6

Effect of MCEO on indomethacin-induced oedema, epithelial disruption, and mucosa erosion in gastric tissues.

Groups	Grading system
	Normal	Oedema and/or vacuolation	Epithelial disruption	Erosion extending to muscularised mucosae
Disease control (distilled water)	0.8 ± 0.4	4.7 ± 0.8	6.5 ± 0.5	4.0 ± 1.0
Ranitidine (100 mg/kg)	2.7 ± 0.4	2.3 ± 0.3	3.5 ± 0.5	0.7 ± 0.7
MCEO (10 mg/kg)	2.3 ± 0.3	2.7 ± 0.4	4.5 ± 0.7	2.0 ± 0.9
MCEO (50 mg/kg)	2.2 ± 0.3	1.7 ± 0.3	3.0 ± 0.8	1.3 ± 0.8
MCEO (100 mg/kg)	2.5 ± 0.2	2.3 ± 0.8	3.0 ± 0.8	1.3 ± 0.8

Data are expressed as mean ± SEM, n = 6, , and . Dunnett’s test as compared to disease control value.