A Novel Herbal Medicine for Dyslipidemia: Assessments in Experimental Models
Table 5
Effects of GANMO on lipid levels in Poloxamer 407-induced dyslipidemia after 1 week of treatment.
Groups
n
Serum lipid levels ( ± SD)
TG (mmol/L)
TC (mmol/L)
HDL-C (mmol/L)
Non-HDL-C (mmol/L)
Model group
10
6.29 ± 1.24
6.91 ± 0.92
1.53 ± 0.13
5.38 ± 0.88
Atorvastatin (100 mg/kg)
10
6.50 ± 1.92
4.70 ± 1.04ΔΔΔ (↓ 32.0%)
1.63 ± 0.19 (↑ 6.5%)
3.07 ± 1.08ΔΔΔ (↓ 42.9%)
GANMO (30.2 g/kg)
10
4.61 ± 1.52Δ (↓ 26.7%)
5.15 ± 0.68ΔΔΔ (↓ 25.5%)
1.74 ± 0.15ΔΔ (↑ 13.7%)
3.41 ± 0.77ΔΔΔ (↓ 36.6%)
GANMO (90.6 g/kg)
10
3.78 ± 0.72ΔΔΔ (↓ 39.9%)
5.04 ± 1.04ΔΔΔ (↓ 27.1%)
1.71 ± 0.21Δ (↑ 11.8%)
3.33 ± 0.93ΔΔΔ (↓ 38.1%)
Note: statistical analysis was done with t-test and ANOVA test, and was considered to be statistically significant; : and compared with the control group; Δ, ΔΔ, ΔΔΔ: ,, and compared with the model group.