Research Article

Network Pharmacology-Based Systematic Analysis of Molecular Mechanisms of Dingji Fumai Decoction for Ventricular Arrhythmia

Table 3

GO and KEGG enrichment analysis of the biofunction modules.

Function modulesDescriptionLog10 ( value)

Module 1ko04020, calcium signaling pathway−22.3027025
GO:0001996, positive regulation of heart rate by epinephrine-norepinephrine−12.3777817
ko04810, regulation of actin cytoskeleton−11.6704785
GO:0043410, positive regulation of MAPK cascade−10.5659921
ko04024, cAMP signaling pathway−9.71878217

Module 2GO:0086010, membrane depolarization during action potential−12.7696584
GO:0006941, striated muscle contraction−11.8188992
ko04261, adrenergic signaling in cardiomyocytes−7.33482642
GO:0019233, sensory perception of pain−5.53543107
GO:0055080, cation homeostasis−3.03192747

Module 3GO:0016098, monoterpenoid metabolic process−13.3868655
GO:0008202, steroid metabolic process−10.1366162
GO:0006690, icosanoid metabolic process−10.0957724
GO:0008203, cholesterol metabolic process−9.58364991
GO:0010035, response to inorganic substance−3.36527057