Investigation of the Mechanism of Traditional Chinese Medicines in Angiogenesis through Network Pharmacology and Data Mining

Figure 7

Molecular docking model. In the 3D structure of ligand-protein complexes, the protein backbone is represented as a cartoon (α-helices in red and ββ-sheets in green), peptide chains are coloured differently, and ligands are displayed in blue. The 2D interaction model shows amino acids circled differently according to their propensity for water; green: hydrophobic residues; purple: polar residues. (a) KDR-6gqq-astragalin; (b) MMP9-1gkc-astragalin; (c) MMP9-1gkc-beta-diosgenin; (d) MMP9-1gkc-beta-sitosterol; (e) PTGS2-5ikq-astragalin; (f) PTGS2-5ikq-kaempferol; (g) PTGS2-5ikq-myricetin; (h) PTGS2-5ikq-quercetin; (i) tp53-1jsp-astragalin.