Research Article

Investigation of the Mechanism of Traditional Chinese Medicines in Angiogenesis through Network Pharmacology and Data Mining

Table 1

Target’s information.

NumberGeneUniProt numberProtein

1PTGS2P35354Prostaglandin G/H synthase 2
2KDRP35968Vascular endothelial growth factor receptor 2
3VEGFAP15692Vascular endothelial growth factor A
4FGF1P05230Acidic fibroblast growth factor
5TP53P04637Cellular tumour antigen p53
6MMP9P14780Matrix metalloproteinase-9
7AKT1P31749RAC-alpha serine/threonine-protein kinase
8MMP2P0825372 kDa type IV collagenase
9CXCL8P10145Interleukin-8
10FGF2P09038Basic fibroblast growth factor
11HIF1AQ16665Hypoxia-inducible factor 1-alpha
12TGFB1P01137Transforming growth factor beta-1
13CCL2P13500C-C motif chemokine 2
14NOS3P29474Nitric oxide synthase, endothelial

Identification of candidate compounds and target-compound network construction.