Antidepressant and Anxiolytic Effects and Subacute Toxicity of the Aerial Parts of Psychotria ankasensis J.B.Hall (Rubiaceae) in Murine Models

Figure 6

Effects of PAE (30, 100, and 300 mg/kg) treatment on the (a) duration and (b) frequency of entry of mice into the central arena of the open field versus the effect of and diazepam (0.3, 1, and 3 mg/kg) on the (c) duration and (d) frequency of entry of mice into the central arena of the open field. Animals in the control group (Ctrl) received only vehicle. Data are presented as group means ± SEM (n = 7). , , and (one-way ANOVA followed by Tukey’s post hoc comparison test.

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