Antidepressant and Anxiolytic Effects and Subacute Toxicity of the Aerial Parts of Psychotria ankasensis J.B.Hall (Rubiaceae) in Murine Models

Table 2

Average organ weight (g) of the Sprague-Dawley rats aged 12–14 weeks.

Parameter (g)	Control	PAE 100 mg/kg	PAE 300 (mg/kg)	PAE 1000 mg/kg
Heart	0.82 ± 0.05	0.62 ± 0.06	0.82 ± 0.03	0.74 ± 0.07
Liver	6.57 ± 0.28	5.18 ± 0.34	6.86 ± 0.36	6.06 ± 0.27
Spleen	0.75 ± 0.03	0.73 ± 0.11	0.91 ± 0.09	0.81 ± 0.06
L. kidney	0.64 ± 0.04	0.53 ± 0.02	0.63 ± 0.05	0.59 ± 0.05
R. kidney	0.64 ± 0.15	0.52 ± 0.04	0.69 ± 0.05	0.60 ± 0.04
Lungs	1.94 ± 0.17	1.38 ± 0.03	1.77 ± 0.08	1.42 ± 0.14
Brain	1.76 ± 0.11	1.81 ± 0.21	1.76 ± 0.04	1.82 ± 0.32

Results are presented as mean ± SEM (n = 5). One-way analysis of variance of all the datasets revealed no statistical significance ().