Evidence-Based Complementary and Alternative Medicine

Research Article

Filtration of Active Components with Antioxidant Activity Based on the Differing Antioxidant Abilities of Schisandrae Sphenantherae Fructus and Schisandrae Chinensis Fructus through UPLC/MS Coupling with Network Pharmacology

Table 2

Components of potential antioxidant activities.


No.	Deduced compound	t_R (min)	Elemental composition	Ion adduction	Calculated mass	Deviation (ppm)	MS²

1	γ-Schizandrin^b,d	2.76	C₂₃H₂₈O₆	[M + H]⁺	401.1959	−0.5	386.1723, 370.1768, 359.1487, 355.1532, 337.1432
2	Espatulenol^b,d	3.40	C₁₅H₂₄O	[M + H]⁺	221.1900	−1.4	203.1795, 193.1587, 175.1481, 163.1481, 147.1168, 133.1012, 107.0858, 95.086
3	Schisandrin^a,b	3.71	C₂₄H₃₂O₇	[M + Na]⁺	455.2040	−2.0	455.2032, 415.2113, 400.1872, 384.1931, 369.1696, 359.1479, 353.1750
4	Tigloylgomisin H^b,d	3.91	C₂₈H₃₆O₈	[M + Na]⁺	523.2302	−0.6	493.1786, 455.2077, 423.1418, 401.1621, 383.1506
5	Gomisin J^b	3.99	C₂₂H₂₈O₆	[M + Na]⁺	411.1778	−1.5	357.1721, 325.1453, 319.1181, 297.1483, 287.0919
5	Gomisin J^b	3.99	C₂₂H₂₈O₆	[M + H]+	389.1943	−3.9	357.1721, 325.1453, 319.1181, 297.1483, 287.0919
6	Schisantherin B^b or angeloylgomisin P^b	4.09	C₂₈H₃₄O₉	[M + Na]⁺	537.2095	−0.7	437.1573,415.1750,371.1498,356.1246
7	Angeloylgomisin P^b or schisantherin B^b	4.12	C₂₈H₃₄O₉	[M + H]⁺	537.2095	−1.5	437.1573,415.1750,371.1498,356.1246
8	Angeloylgomisin H^b,d	4.13	C₂₈H₃₆O₈	[M + Na]⁺	523.2302	−0.6	416.1823, 387.1798, 372.1564, 356.1614, 342.1453, 326.1503
9	Schilancifolignan A^c,d	4.25	C₂₄H₃₀O₇	[M + H]⁺	431.2064	−1.2	493.1840,455.2039,423.1422,383.1489
10	Schisantherin C^b	4.50	C₂₈H₃₄O₉	[M + H]⁺	515.2275	−1.4	385.1649, 355.1543, 343.1183, 316.0944
11	Gomisin K1^b,d	4.65	C₂₃H₃₀O₆	[M + Na]⁺	425.1934	−0.7	410.1701, 395.1464, 379.1516
12	Gomisin E^b	4.97	C₂₈H₃₄O₉	[M + H]⁺	515.2275	−0.2	469.2206, 385.1646, 355.1538, 343.1179, 316.0941
13	Gomisin M1^b,d	5.07	C₂₂H₂₆O₆	[M + Na]⁺	409.1621	−1.0	394.1393, 363.1185, 333.1724
14	Schisandrin B^a,b,d	5.37	C₂₃H₂₈O₆	[M + H]⁺	401.1959	−0.7	300.0990,270.0883,242.0936,331.1174,386.1723,401.1953

The superscript “a” represents compounds identified by standard, superscript “b” represents compounds identified by literature reports, superscript “c” represents compounds speculated based on its MS² fragments, and superscript “d” represents compounds solely found in SCF.