SAPA was taken orally three times a day in control group; amount was reduced after remission. Oral TXYF was taken twice a day in treatment group on the basis of control group drug halved. The course of treatment was 3 months.
Incidence of adverse reactions and level of C-reactive protein
The CRP level of treatment group was lower than the control group (), and there were fewer adverse events in treatment group ().
Oral TXYF in combination with THXWT decoction twice a day in treatment group and SAPA three times a day in control group for 30 days; both groups were followed up for 1 year.
Clinical and electronic colonoscopy efficacy and recurrence rate
The clinical and colonoscopy efficacy rate in treatment group is higher than control group (). Recurrence rate under endoscopy in treatment group is lower than control group ().
SAPA four times a day and prednisone 3 times a day in control group, oral TXYF in combination with SLBZS twice a day in treatment group. The total course of treatment was 4 weeks.
Clinical and electronic colonoscopy efficacy
The clinical and electronic colonoscopy efficacy is superior in treatment group than control group ().
Mesalazine four times a day in control group, TXYF is orally given to the treatment group twice a day on the basis of control group, the total course of treatment was 16 weeks.
Clinical efficacy rate and incidence of adverse reactions
The clinical efficacy rate is higher in treatment group than control (); there is no significant difference in the incidence of adverse reaction ().
Mesalazine anal suppository 3 times a day in control group. Oral TXYF twice a day in the treatment group on the basis of control group. The course of treatment was 60 days.
Clinical efficacy rate and interleukin level in serum
The effective rate is higher in treatment group than control group (), the level of IL-10 in treatment group is higher than control group, and the lever of IL-17 is lower ().
SAPA three times a day in control group, TXYF is orally given to the treatment group on the basis of control group, the total course of treatment was 8 weeks.
Clinical efficacy rate, DAI, ESR, and CRP
The clinical effective rate was higher in treatment group than control group (). The levels of DAI, ESR, and CRP improved significantly compared with the control group ().
SAPA 3 times a day and bifidobacterium triplex capsule 2 times a day in control group. TXYF is orally given to the treatment group on the basis of control group, the total course of treatment was 8 weeks.
Clinical efficacy rate and serological markers of inflammation
The effective rate was higher in treatment group than control group (); the levels of IL-1, IL-8, and TNF-α in the treatment group were significantly lower than control group ().
TXYF: Tong Xie Yao Fang; THXWT: Tao Hong Si Wu decoction; SLZBS: Shen Ling Bai Zhu powder; DAI: disease activity index; ESR: erythrocyte sedimentation rate; CRP: C-reactive protein; UC; ulcerative colitis; IL-1: interleukin-1; IL-8: interleukin-8; IL-10: interleukin-10; IL-17: interleukin-17; SASP: salicylazosulfapyridine; SJZT: Sijunzi decoction; and TNF-α: tumor necrosis factor-α.
