Baihe Jizihuang Tang Ameliorates Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior: Integrating Network Pharmacology and Brain-Gut Axis Evaluation

Figure 9

Expression level of BDNF and TrkB in the hippocampus of rats. No. 1–6 in protein band plot correspond to the Control group, CUMS group, CUMS + BHT 2.7 g/kg group, CUMS + BHT 5.4 g/kg group, CUMS + BHT 10.8 g/kg group, and CUMS + Flu 1.8 mg/kg group, respectively. Control represents the control group; CUMS represents the CUMS group; CUMS + Flu represents the intervention of 1.8 mg/kg fluoxetine on CUMS rats; and CUMS + BHT represents the intervention of 2.7 g/kg, 5.4 g/kg, and 10.8 g/kg BHT on CUMS rats. (a) Quantitative analysis of BDNF protein expression in hippocampus after treatment of BHT. (b) Quantitative analysis of TrkB protein expression in hippocampus after treatment of BHT. The statistical method was one-way ANOVA (n = 3). Compared with the control group, , and compared with the CUMS, .

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