Baihe Jizihuang Tang Ameliorates Chronic Unpredictable Mild Stress-Induced Depression-Like Behavior: Integrating Network Pharmacology and Brain-Gut Axis Evaluation

Table 2

Key pharmacodynamic molecules and topological parameters in BHT.

Herb	Molecule ID	Molecule name	Molecular weight (g·mol^−1)	OB (%)	DL	Degree	BC	CC
JZH, BH	MOL4	Beta-sitosterol	414.79	36.91	0.75	21	0.06750618	0.42857143
JZH	MOL5	Oleic acid	282.52	33.13	0.14	19	0.04278457	0.39923954
BH	MOL19	Stigmasterol	412.77	43.83	0.76	17	0.0374903	0.40540541
BH	MOL27	Regaloside E	458.46	7	0.55	15	0.01716852	0.3633218
JZH	MOL9	Arachidonic acid	304.52	45.57	0.2	15	0.03220645	0.39622642
BH	MOL25	Regaloside A	400.42	11.38	0.46	11	0.00810584	0.35353535
BH	MOL26	Regaloside B	442.46	15.63	0.51	11	0.00775733	0.35353535
JZH	MOL16	Glutamic acid	147.15	6.66	0.02	10	0.01255659	0.37366548
BH	MOL28	Regaloside C	416.4	0	0	9	0.00618232	0.34653465
JZH	MOL15	Aspartic acid	133.12	79.74	0.02	7	0.00657208	0.36082474
JZH	MOL1	Palmitic acid	256.48	19.3	0.1	6	0.00520702	0.3633218
JZH	MOL14	Serine	105.11	98.47	0.01	6	0.00475422	0.36082474
JZH	MOL2	Linoleic acid	280.5	41.9	0.14	6	0.00386105	0.3633218
BH	MOL22	3-Demethylcolchicine	385.45	39.34	0.57	6	0.00931012	0.36842105
JZH	MOL17	Leucine	131.2	72.92	0.01	4	0.00166033	0.3559322
JZH	MOL8	Myristic acid	228.42	21.18	0.07	4	0.00196339	0.35836177
JZH	MOL10	Zoomaric acid	254.46	35.78	0.1	3	7.23E − 04	0.3559322
JZH	MOL12	Linolenic acid	278.48	45.01	0.15	3	7.23E − 04	0.3559322
JZH	MOL3	Ergosterol	396.72	14.29	0.72	3	0.00260936	0.35117057
JZH	MOL6	Stearic acid	284.54	17.83	0.14	3	7.23E − 04	0.3559322
JZH	MOL11	Lanosterol	426.8	42.12	0.75	2	0.00105441	0.35117057
BH	MOL20	Isopimaric acid	302.5	36.2	0.28	2	0.00123783	0.35117057
BH	MOL23	26-O-Β-D-Glucopyranosyl-3Β, 26-dihydroxy-5-cholesten-16, 22-dioxo-3-O-Α-L-rhamnopyranosyl-(1⟶2)-Β-D-glucopyranoside_Qt	430.69	35.11	0.81	2	0.00107903	0.33546326
JZH	MOL7	Cholesterol	386.73	37.87	0.68	2	0.00105441	0.35117057
JZH	MOL13	Desmosterol	384.71	13.23	0.68	1	0	0.30259366
JZH	MOL18	Lysine	146.22	29.33	0.02	1	0	0.30259366
BH	MOL21	26-O-beta-D-Glucopyranosyl-3Beta,26-dihydroxy-choleslen-16,22-dioxo-3-O-Alpha-L-rhamnopyranosyl-(1-2)-beta-D-glucopyranoside_Qt	432.71	32.43	0.8	1	0	0.27559055
BH	MOL24	26-O-Β-D-Glucopyranosyl-3Β, 26-dihydroxy-cholestan-16, 22-dioxo-3-O-Α-L-rhamnopyranosyl-(1⟶2)-Β-D-glucopyranoside_Qt	432.71	32.43	0.8	1	0	0.27559055