Overexpression of MAL2 Correlates with Immune Infiltration and Poor Prognosis in Breast Cancer

Table 4

Univariate and multivariate analyses of overall survival in breast cancer.

Parameter	Univariate analysis			Multivariate analysis
	Hazard ratio	95% CI	value	Hazard ratio	95% CI	value
Age (≥40/<40)	1.564	0.568	0.387	1.871	0.672	0.230
		–4.306			–5.205
Stage (III + IV/I + II)	1.745	1.376–2.212	<0.001	1.473	1.032	0.033
					—
					2.102
T classification (T3 + T4/T1 + T2)	1.595	1.220–2.084	0.001	1.394	0.993–1.956	0.055
N classification (N1 + N2 + N3/N0)	1.675	1.023–2.742	0.040	0.992	0.542–1.816	0.979
M classification (M1/M0)	7.873	3.378–18.351	<0.001	3.093	1.215–7.878	0.018
Estrogen receptor (positive/negative)	0.612	0.369–1.015	0.057	0.506	0.220–1.160	0.107
Progesterone receptor (positive/negative)	0.748	0.465–1.205	0.233	0.932	0.425–2.047	0.862
HER2 (positive/negative)	1.553	0.914–2.638	0.104	1.256	0.723–2.180	0.419
MAL2 (high/low)	1.626	1.012–2.612	0.045	1.792	1.093–2.937	0.021