Exploring the Therapeutic Mechanisms of Huzhang–Shanzha Herb Pair against Coronary Heart Disease by Network Pharmacology and Molecular Docking

Table 1

Key components and target molecular docking information of HSHP.

Targets	Protein	Ingredient	Id	Binding free energy (kcal/mol)
TNF	TNF	3,5-Dimethyl-4-methoxybenzoic acid	TCMID:25838	−7.8
TNF	TNF	Caffeic acid dimethyl ether	TCMID:23381	−7.6
NF-κB	NF-κB	3,5-Dimethyl-4-methoxybenzoic acid	TCMID:25838	−4.5
NF-κB	NF-κB	Simvastatin	CID:54454	−6.4
ESR1	ESR1	Emodin	TCMID:6775	−8.2
ESR1	ESR1	Polygalacic acid	TCMID:25027	−7.4
ESR1	ESR1	Quillaic acid	TCMID:31893	−7.9
ESR1	ESR1	Resveratrol	TCMID:18628	−7.2
ESR1	ESR1	Simvastatin	CID:54454	−9.3
ESR1	ESR1	Ursolic acid	TCMID:22254	−7.9