Qindan Capsule Attenuates Myocardial Hypertrophy and Fibrosis in Pressure Overload-Induced Mice Involving mTOR and TGF-β1/Smad Signaling Pathway Inhibition

Figure 5

Effects of QC on the cardiac mTOR signaling pathway after TAC surgery in mice. (a) Representative results of protein levels and phosphorylation levels of mTOR, 70S6K, and 4EBP1. Quantification of ratios of p-mTOR to mTOR (b), p-70S6K to 70S6K (c), and p-4EBP1 to 4EBP1 (d). and vs. sham group. , , and vs. TAC group. Data are presented as mean ± SEM and n = 3.

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