Qindan Capsule Attenuates Myocardial Hypertrophy and Fibrosis in Pressure Overload-Induced Mice Involving mTOR and TGF-<i>β</i>1/Smad Signaling Pathway Inhibition

<div>Effects of QC on the cardiac TGF-<i>β</i>1/Smad pathway after TAC surgery in mice. (a) Representative results of the protein levels of TGF-<i>β</i>1, collagen I, and GAPDH and phosphorylation levels of Smad2 and Smad3. 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d="M384 0V27C293 34 287 42 287 114V635C232 613 172 594 109 583V559L157 557C201 555 205 550 205 499V114C205 42 199 34 109 27V0H384Z"></path></g></svg> vs. TAC group. Data are presented as mean ± SEM and <i>n</i> = 3.</div>

Evidence-Based Complementary and Alternative Medicine

fig6

Figure 6

Figure 6: Qindan Capsule Attenuates Myocardial Hypertrophy and Fibrosis in Pressure Overload-Induced Mice Involving mTOR and TGF-<i>β</i>1/Smad Signaling Pathway Inhibition 

Figure 6 | Qindan Capsule Attenuates Myocardial Hypertrophy and Fibrosis in Pressure Overload-Induced Mice Involving mTOR and TGF-β1/Smad Signaling Pathway Inhibition 