Spasmolytic Effect of Grewia asiatica Fruit Extract on Isolated Smooth Muscles is Mediated via Multiple Pathways

Figure 4

The graph showing the vasodilator effect of Grewia asiatica 70% methanolic extract (Ga.Cr) on isolated endothelium-intact rat aorta tissue preparation, with and without L-NG-nitro arginine methyl ester 0.1 mM (L-NAME). The vasorelaxant effect was quantified upon phenylephrine 1 μM (PE) spasmogenicity. The vasorelaxant action of the extract was determined as a percent of PE-induced contractions (results are mean ± SEM for 4 observations).