Research Article

Antiobesity and Antidiabetic Effects of Portulaca oleracea Powder Intake in High-Fat Diet-Induced Obese C57BL/6 Mice

Table 3

Organ weight and unit organ weight of C57BL/6 mice fed the experimental diets.

Group(1)Total organ weight (g)Total unit organ weight (mg/g BW)
CONHFDHFD + PO5%HFD + PO10%CONHFDHFD + PO5\%HFD + PO10%

Liver0.99 ± 0.012(2)b1.08 ± 0.046a1.03 ± 0.024ab0.98 ± 0.018b35.35 ± 0.331a27.43 ± 0.598b27.50 ± 0.712b29.06 ± 1.124b
Heart0.10 ± 0.005b0.13 ± 0.006a0.13 ± 0.006a0.12 ± 0.003a3.64 ± 0.197NS3.40 ± 0.1763.56 ± 0.1573.63 ± 0.199
Kidney0.33 ± 0.004b0.37 ± 0.008a0.37 ± 0.009a0.36 ± 0.013a11.79 ± 0.182a9.39 ± 0.363c9.91 ± 0.376bc10.70 ± 0.535ab
Spleen0.05 ± 0.003b0.06 ± 0.003a0.06 ± 0.003a0.06 ± 0.002a1.61 ± 0.089NS1.61 ± 00931.59 ± 0.0491.74 ± 0.104
Testis0.19 ± 0.013NS0.19 ± 0.0110.18 ± 0.0150.18 ± 0.0086.66 ± 0.523a4.84 ± 0.413b4.82 ± 0.471b5.34 ± 0.423ab
Epididymidis0.02 ± 0.002NS0.02 ± 0.0020.02 ± 0.0020.02 ± 0.0020.58 ± 0.065NS0.49 ± 0.0650.47 ± 0.0470.52 ± 0.057
Perirenal fats0.51 ± 0.055c2.15 ± 0.177a1.95 ± 0.093a0.34 ± 0.146b18.23 ± 1.878c54.42 ± 3.006a51.79 ± 2.673a38.89 ± 4.002b
Epididymal fats tissue0.02 ± 0.002b0.03 ± 0.003a0.03 ± 0.002a0.02 ± 0.003b0.63 ± 0.061NS0.77 ± 0.0700.77 ± 0.0650.63 ± 0.089
Brown fats tissue0.08 ± 0.004bc0.10 ± 0.011ab0.10 ± 0.008a0.07 ± 0.005c2.69 ± 0.137a2.45 ± 0.240ab2.69 ± 0.209a2.04 ± 0.161b

(1)CON: control diet; HFD: high fat diet; HFD + PO5%: high fat diet + 5% P. oleracea powder; HFD + PO10%: high fat diet + 10% P. oleracea powder. (2)Values are the mean ± SE (n = 8/group). (a–c)Values with different superscript in the same row are significantly different at by Duncan’s multiple range test. NS: not significant.