CHM (Semen Cuscutae 10 g, Radix Dipsaci 10 g, Colla Corii Asini 6 g, Ramie root 10 g, Cortex Eucommiae 10 g) placed on CV 8 for 4–6 h per day and combined with comparator
Progesterone, 40 mg, IM, QD, until symptoms disappear, and change to 20 mg, IM, QD, 7 days
RCT
90.0%
The combination can shorten the treatment time, increase serum P level, improve luteal function, prevent subsequent miscarriage, and increase the successful pregnancy rate.
CHM (Cortex Eucommiae 10 g, Ramie root 10 g, Radix Dipsaci 10 g, Semen Cuscutae 10 g, Colla Corii Asini 6 g) placed on CV 8 for 6 h per day and combined with comparator
Progesterone, 20 mg, IM, QD, 7 days
RCT
89.2%
The combination increased the efficacy rate and improved the clinical symptoms of threatened miscarriage.
CHM (Semen Cuscutae 10 g, Radix Dipsaci 10 g, Colla Corii Asini 6 g, Ramie root 10 g, Cortex Eucommiae 10 g) placed on the acupoints for 4 h per day, combined with Bushen Jianpi decoction, PO, BID, and comparator
Progesterone, 20 mg, IM, QD
RCT
93.94%
The combination can improve threatened miscarriage by inhibiting the secretion of INF-γ, promoting the secretion of IL-10, correcting the pathological shift of Th1/Th2 cytokine balance, and increasing the secretion of hCG and P.
hCG 1000 IU, injected at ST36 and massaged for 3–5 min, alternating on both sides, QOD, 7–10 days, or until a week after symptoms disappear
hCG 1000 IU, IM, QOD, 7–10 days, or until a week after symptoms disappear
RCT
91.38–91.7%
It increased the levels of hCG, E2, and P; decreased the miscarriage rate and treatment time; reduced the amount of conventional medication; and promoted the development of the fetal sac.
Moxibustion was performed at a distance of 3-4 cm from the patient’s acupoints to make the patient feel moderate heat, 20–30 min, QD. Combined with dydrogesterone, PO, first dose is 40 mg followed by 10 mg, Q8H, until the symptoms disappear
Progesterone, 40 mg, IM, QD, 14 days
RCT
Successful pregnancy rate: 87.5%
The combinations can increase hCG and P, improve symptoms, and increase the successful pregnancy rate.