Review Article

A Systematic Review of Antiaging Effects of 23 Traditional Chinese Medicines

Table 2

Antiaging research of TCM or its active components based on other animal or cell models.

Types of TCMRole formAnimal models or cell linesInduced wayPathwaysRef.

Scutellaria baicalensis Georgi flowersRatD-galactose-inducedGlutamine–glutamate metabolic pathway[40]
Rhodiola roseaAqueous extractSilkworm; Bombyx moriIIS[41]
Gentiana rigescens FranchGentiopicroside (GPS)YeastMitochondrial autophagy pathway; antioxidant pathway[42]
Zanthoxylum bungeanum Maxim (Rutaceae)Aqueous extract, volatile oil (VOZ), petroleum ether (PEZ), and methylene chlorideMiceD-galactose-inducedPI3K/Akt/Nrf2 signaling pathway[43]
Nigella sativaFixed oilMiceD-galactose-inducedAntioxidant pathway; antiapoptotic pathway[44]
Safflower seedOilHaCaT cells and HDFUltraviolet B-induced[45]
PomegranateDried pomegranate juiceMiceUVB-induced[46]
Agastache rugosa KuntzeHot water extractionHaCaTUVB-induced[47]
Plumbago zeylanicaDermal papilla cells[48]
GinsengGinsenoside Rb1Human umbilical vein endothelial cells (HUVEC)H2O2-inducedSIRT signaling[49]