Alkaloid Extract of Moringa oleifera Lam. Exerts Antitumor Activity in Human Non-Small-Cell Lung Cancer via Modulation of the JAK2/STAT3 Signaling Pathway

Figure 2

MOAE induces apoptosis in A549 cells. A549 cells were treated with MOAE (0, 100, or 200 μg/mL) for 48 h. (a) The percentage of apoptotic cells was determined by flow cytometry. (b) The percentage of apoptotic cells in each treatment group. (c) The expression of the apoptosis-related proteins caspase-3 and caspase-9 in A549 cells was measured by western blotting assay, with β-actin used as the loading control. Quantification of the relative levels of caspase-3 and caspase-9 proteins. The results are expressed as the mean ± SEM of three independent experiments. and vs. 0 μg/mL.

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