Alkaloid Extract of Moringa oleifera Lam. Exerts Antitumor Activity in Human Non-Small-Cell Lung Cancer via Modulation of the JAK2/STAT3 Signaling Pathway

Figure 3

MOAE induces cell cycle arrest in A549 cells. A549 cells were treated with MOAE (0, 100, or 200 μg/mL) for 48 h. (a) The cell cycle of A549 cells was analyzed by flow cytometry; (b) statistical analysis of three independent experiments. (c) The expression of the cell cycle-related proteins cyclin D1, cyclin E, and p21 in A549 cells was assessed by western blotting assay, with β-actin used as the loading control. Quantification of the relative levels of the proteins cyclin D1, cyclin E, and p21. The results are expressed as the mean ± SEM of three independent experiments. , , and vs. 0 μg/mL.

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