Preparation and Characterization of MUC-30-Loaded Polymeric Micelles against MCF-7 Cell Lines Using Molecular Docking Methods and In Vitro Study

Table 1

Micelle size, drug loading content (% DLC), encapsulation efficiency (% EE), and yields (% yields) of MUC30-loaded PEG-b-PCL and PEG-b-PLA micelles.

Block copolymer	Initial ratio of MUC-30 : polymer	Micelle size (nm)	DLC (%)	EE (%)	Yield (%)
PEG (5k)-b-PCL (5k)	1 : 9	39.76 ± 8.50	10.1 ± 0.1	70.6 ± 4.4	69.9 ± 4.0
	2 : 8	45.61 ± 3.34	19.1 ± 0.8	53.0 ± 1.7	54.0 ± 0.1
	3 : 7	55.68 ± 2.36	29.6 ± 0.3	64.8 ± 5.3	65.7 ± 5.0
PEG (5k)-b-PLA (5k)	1 : 9	52.67 ± 3.74	9.7 ± 0.3	55.6 ± 0.3	58.2 ± 1.8
	2 : 8	80.77 ± 2.77	18.9 ± 0.2	53.3 ± 1.0	56.5 ± 0.6
	3 : 7	93.1 ± 3.5	27.3 ± 0.7	9.4 ± 0.9	10.3 ± 0.8