Exploring the Mechanisms of Arsenic Trioxide (Pishuang) in Hepatocellular Carcinoma Based on Network Pharmacology

Figure 4

GO analysis. There are four circles in the figure. From outside to inside, the first circle is the classification of enrichment. Different colors represent different classifications. The second circle shows the number of background genes and value. The more the genes, the longer the bars; the smaller the value, redder the color. The third circle is the total number of prospective genes. The fourth circle represents rich factor, which indicates the ratio of genes in the current study versus the total genes in the term. GO:0071456: cellular response to hypoxia; GO:0008283: cell proliferation; GO:0042981: regulation of apoptotic process; GO:0034612: response to tumor necrosis factor; GO:0001525: angiogenesis; GO:2000773: negative regulation of cellular senescence; GO:0035729: cellular response to hepatocyte growth factor stimulus; GO:0005741: mitochondrial outer membrane; GO:0031090: organelle membrane; GO:0005657: replication fork; GO:0090575: RNA polymerase II transcription factor complex; GO:0000784: nuclear chromosome, telomeric region; GO:0035098: ESC/E(Z) complex; GO:0019899: enzyme binding; GO:0008134: transcription factor binding; GO:0019901: protein kinase binding; GO:0051059: NF-kappa B binding; GO:0005524: ATP binding; GO:0002039: p53 binding; GO:0004674: protein serine/threonine kinase activity.