Electroacupuncture Alleviates Hyperalgesia by Regulating CB1 Receptor of Spinal Cord in Incisional Neck Pain Rats

Figure 2

Effect of EA on the expression levels of endocannabinoid receptor CB1 (a, c, e, g) and CB2 (b, d, f, h) proteins at the 3 time points after modeling in the dorsal portion of the cervical spinal cord (C2-C5) in neck incisional pain rats. Representative gel images showing the protein level of CB1 (a) and CB2 (b) receptors in the cervical spinal cord tissues in different groups: (1) control group, (2) model group, (3) EA LI18 group, (4) EA LI4-PC6 group, and (5) EA ST36-GB34 group. The expression of CB1 protein was significantly increased at 48 h in the model group (vs the control group), and at 4, 24, and 48 h in the EA LI18 group (VS the model group), and the expression levels of CB2 protein at 4, 24, and 48 h had no notable changes after modeling (vs the control group) and after EA of the 3 acupoint groups (vs the model group). Data are expressed as means ± SD (n = 8).  < 0.05, vs the control group, ^{^} < 0.05, vs the model group.

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