Research Article

Chemical Analysis of the Ingredients of 20% Aqueous Ethanol Extract of Nardostachys jatamansi through Phytochemical Study and Evaluation of Anti-Neuroinflammatory Component

Table 2

Inhibitory effects of NJ20 on LPS-induced pro-inflammatory mediators and cytokines in BV2 and primary microglial cells.

Proinflammatory mediators and cytokinesBV2 microglial cells IC50 (μg/mL)Primary microglial cells IC50 (μg/mL)

NO12.57 ± 0.1028.83 ± 1.08
PGE215.36 ± 2.767.14 ± 0.71
IL-1β12.69 ± 1.0625.62 ± 0.93
IL-614.15 ± 0.6621.12 ± 2.53
TNF-α13.52 ± 3.2029.90 ± 6.77