Exploring the Potential Mechanism of Shennao Fuyuan Tang for Ischemic Stroke Based on Network Pharmacology and Molecular Docking

Table 1

Active components of SNFYT.

Herb	Mol ID	Molecule name	MW	OB (%)	DL
SZY	MOL001494	Mandenol	308.56	42.00	0.19
SZY	MOL001495	Ethyl linolenate	306.54	46.10	0.20
SZY	MOL001771	Poriferast-5-en-3beta-ol	414.79	36.91	0.75
SZY	MOL002879	Diop	390.62	43.59	0.39
SZY	MOL003137	Leucanthoside	462.44	32.12	0.78
SZY	MOL005360	Malkangunin	432.56	57.71	0.63
SZY	MOL005481	2,6,10,14,18-Pentamethylicosa-2,6,10,14,18-Pentaene	342.67	33.40	0.24
SZY	MOL005486	3,4-Dehydrolycopen-16-al	548.92	46.64	0.49
SZY	MOL005489	3,6-Digalloylglucose	484.40	31.42	0.66
SZY	MOL005503	Cornudentanone	378.56	39.66	0.33
SZY	MOL005530	Hydroxygenkwanin	300.28	36.47	0.27
SZY	MOL005531	Telocinobufagin	402.58	69.99	0.79
SZY	MOL008457	Tetrahydroalstonine	352.47	32.42	0.81
SZY	MOL000554	Gallic acid-3-O-(6′-O-galloyl)-glucoside	484.40	30.25	0.67
SZY	MOL005552	Gemin D	634.49	68.83	0.56
SZY	MOL005557	Lanosta-8, 24-dien-3-ol, 3-acetate	468.84	44.30	0.82
SY	MOL001559	Piperlonguminine	273.36	30.71	0.18
SY	MOL001736	(-)-Taxifolin	304.27	60.51	0.27
SY	MOL000310	Denudatin B	356.45	61.47	0.38
SY	MOL000322	Kadsurenone	356.45	54.72	0.38
SY	MOL005429	Hancinol	372.50	64.01	0.37
SY	MOL005430	Hancinone C	400.51	59.05	0.39
SY	MOL005435	24-Methylcholest-5-enyl-3belta-O-glucopyranoside_qt	400.76	37.58	0.72
SY	MOL005438	Campesterol	400.76	37.58	0.71
SY	MOL005440	Isofucosterol	412.77	43.78	0.76
SY	MOL005458	Dioscoreside C_qt	444.72	36.38	0.87
SY	MOL000546	Diosgenin	414.69	80.88	0.81
SY	MOL005461	Doradexanthin	584.96	38.16	0.54
SY	MOL005463	Methylcimicifugoside_qt	556.81	31.69	0.24
SY	MOL005465	AIDS180907	394.45	45.33	0.77
SY	MOL000953	CLR	386.73	37.87	0.68
HQ	MOL000239	Jaranol	314.31	50.83	0.29
HQ	MOL000296	Hederagenin	414.79	36.91	0.75
HQ	MOL000033	(3S, 8S, 9S, 10R, 13R, 14S, 17R)-10,13-Dimethyl-17-[(2R, 5S)-5-propan-2-yloctan-2-yl]-2, 3, 4, 7, 8, 9, 11, 12, 14, 15, 16, 17-dodecahydro-1H-cyclopenta [a] phenanthren-3-ol	428.82	36.23	0.78
HQ	MOL000354	Isorhamnetin	316.28	49.60	0.31
HQ	MOL000371	3, 9-di-O-methylnissolin	314.36	53.74	0.48
HQ	MOL000374	5′-Hydroxyiso-muronulatol-2′, 5′-di-O-glucoside	642.67	41.72	0.69
HQ	MOL000378	7-O-methylisomucronulatol	316.38	74.69	0.30
HQ	MOL000379	9, 10-Dimethoxypterocarpan-3-O-β-D-glucoside	462.49	36.74	0.92
HQ	MOL000380	(6aR, 11aR)-9, 10-Dimethoxy-6a, 11a-dihydro-6H-benzofurano [3, 2-c] chromen-3-ol	300.33	64.26	0.42
HQ	MOL000387	Bifendate	418.38	31.10	0.67
HQ	MOL000392	Formononetin	268.28	69.67	0.21
HQ	MOL000398	Isoflavanone	316.33	109.99	0.30
HQ	MOL000417	Calycosin	284.28	47.75	0.24
HQ	MOL000433	FA	441.45	68.96	0.71
HQ	MOL000438	(3R)-3-(2-hydroxy-3, 4-dimethoxyphenyl) chroman-7-ol	302.35	67.67	0.26
HQ	MOL000439	Isomucronulatol-7, 2′-di-O-glucosiole	626.67	49.28	0.62
HQ	MOL000442	1, 7-Dihydroxy-3, 9-dimethoxy pterocarpene	314.31	39.05	0.48
MDP	MOL007369	4-O-methylpaeoniflorin_qt	332.38	67.24	0.43
MDP	MOL007374	5-[[5-(4-Methoxyphenyl)-2-furyl] methylene] barbituric acid	312.30	43.44	0.30
MDP	MOL007382	Mudanpioside-h_qt 2	336.37	42.36	0.37
MDP	MOL007384	Paeonidanin_qt	330.41	65.31	0.35
CS	MOL001918	Paeoniflorgenone	318.35	87.59	0.37
CS	MOL001921	Lactiflorin	462.49	49.12	0.80
CS	MOL001924	Paeoniflorin	480.51	53.87	0.79
CS	MOL002714	Baicalein	270.25	33.52	0.21
CS	MOL002776	Baicalin	446.39	40.12	0.75
CS	MOL004355	Spinasterol	412.77	42.98	0.76
CS	MOL006990	(1S, 2S, 4R)-trans-2-Hydroxy-1, 8-cineole-B-D-glucopyranoside	332.44	30.25	0.27
CS	MOL006992	(2R, 3R)-4-methoxyl-distylin	318.30	59.98	0.30
CS	MOL006994	1-O-beta-d-glucopyranosyl-8-o-benzoylpaeonisuffrone_qt	302.35	36.01	0.30
CS	MOL006996	1-O-beta-d-glucopyranosylpaeonisuffrone_qt	332.38	65.08	0.35
CS	MOL006999	Stigmast-7-en-3-ol	414.79	37.42	0.75
CS	MOL007004	Albiflorin	480.51	30.25	0.77
CS	MOL007005	Albiflorin_qt	318.35	48.70	0.33
CS	MOL007008	4-Ethyl-paeoniflorin_qt	332.38	56.87	0.44
CS	MOL007012	4-O-methyl-paeoniflorin_qt	332.38	56.70	0.43
CS	MOL007014	8-Debenzoylpaeonidanin	390.43	31.74	0.45
CS	MOL007016	Paeoniflorigenone	318.35	65.33	0.37
CS	MOL007018	9-Ethyl-neo-paeoniaflorin A_qt	334.40	64.42	0.30
CS	MOL007022	EvofolinB	318.35	64.74	0.22
CS	MOL007025	Isobenzoylpaeoniflorin	584.62	31.14	0.54
CS	MOL005043	Campest-5-en-3beta-ol	400.76	37.58	0.71
HJT	MOL002823	Herbacetin	302.25	36.07	0.27
HJT	MOL004020	Gossypetin	318.25	35.00	0.31
DL	—	Leucinum	—	—	—
DL	—	GLY	—	—	—
DL	—	L-valin	—	—	—
DL	—	Palmitic acid	—	—	—
DL	—	EIC	—	—	—
DL	—	Adenine	—	—	—
DL	—	HX	—	—	—
DL	—	GUN	—	—	—
SDH/CS/MDP/SZY	MOL000359	Sitosterol	414.79	36.91	0.75
SDH/CS/DG/
SY/SZY	MOL000449	Stigmasterol	412.77	43.83	0.76
SZY/CS	MOL002883	Ethyl oleate (NF)	310.58	32.40	0.19
SZY/DG/CS	MOL000358	Beta-sitosterol	414.79	36.91	0.75
HQ/MDP	MOL000211	Mairin	456.78	55.38	0.78
HQ/MDP/HJT	MOL000422	Kaempferol	286.25	41.88	0.24
HQ/MDP/HJT	MOL000098	Quercetin	302.25	46.43	0.28
MDP/CS	MOL001925	paeoniflorin_qt	318.35	68.18	0.40
MDP/CS	MOL000492	(+)-Catechin	290.29	54.83	0.24
MDP/CS	MOL007003	Benzoyl paeoniflorin	584.62	31.14	0.54
CS/HJT	MOL001002	Ellagic acid	302.20	43.06	0.43