Mechanism of Huo-Xue-Qu-Yu Formula in Treating Nonalcoholic Hepatic Steatosis by Regulating Lipid Metabolism and Oxidative Stress in Rats

Table 1

Effects of HXQYF on morphological changes in NAFLD rats’ liver tissues.

Groups	Dose (mg/kg)	Steatosis					Inflammatory cells infiltration
		0	1	2	3	4	0	1	2	3
Normal	—	8	—	—	—	—	6	2	—	—
HFD	—	—	—	1	5	2	—	4	2	2
HXQYF	90	1	4	2	1	—	1	6	1	—
ESS	136.8	—	2	5	1	—	1	5	2	—

Criteria of histopathological scores are as follows: fat: hepatocytes fat containing less 5% (score 0); hepatocytes fat containing 5% to 30% (score 1); hepatocytes fat containing 31% to 50% (score 2); hepatocytes fat containing 51% to 75% (score 3); and hepatocytes fat containing more than 75% (score 4). Lobular inflammation: no inflammation and necrosis (score 0); mild injury/inflammation (score 1); moderate injury/inflammation (score 2); and marked injury/inflammation (score 3). n = 8 in each group.