Research Article

Efficacy and Safety of Chuanxiong Qingnao Granule in Patients with Migraine: A Randomized, Double-Blind, Placebo-Controlled Trial

Table 3

Efficacy measurements of participants at week 12.

CharacteristicTreatment (n = 172)Control (n = 174) value

Percentage of patients with ≥50% reduction in frequency of headache, n (%)123 (71.5)21 (12.1)<0.001
Frequency of headache attack, mean (SD)2.81 ± 0.694.45 ± 1.03<0.001
Days of headache attack, mean (SD)4.99 ± 1.546.09 ± 1.48<0.001
VAS, mean (SD)4.81 ± 1.576.17 ± 1.65<0.001
FSS, mean (SD)23.34 ± 8.3627.29 ± 7.62<0.001
HAMD, mean (SD)14.13 ± 5.5516.78 ± 6.79<0.001
MIDAS, mean (SD)13.73 ± 4.2917.52 ± 5.51<0.001