Systematically Deciphering the Pharmacological Mechanism of Fructus Aurantii via Network Pharmacology

Figure 5

Network pharmacology analysis through the protein-protein interaction of predicted protein targets of FA. (a) The network nodes were predicted proteins and the edges represented the functional associations. (b) The colors of nodes were changed with the betweenness centrality, the size of nodes was changed with the degree, and the colors of edge were changed with the combined score. The degree of each node was defined by the number of connections that the node has. The betweenness centrality of a node reflects the amount of control that this node exerts over the interactions of other nodes in the network.

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