Systematically Deciphering the Pharmacological Mechanism of Fructus Aurantii via Network Pharmacology

Figure 6

The molecule docking results of 5 bioactive compounds in FA with 20 key target proteins in enriched pathways and PPI network. The list of potential target proteins is as follows: 1-Akt1; 2-BAX; 3-BCL2; 4-caspase 3; 5-IL-2; 6-INSR; 7-JNU; 8-MAPK1; 9-MAPK3-ERK; 10-MAPK8-JNK; 11-MDM2; 12-MMP9; 13-NOS2; 14-PPARA; 15-PPARG; 16-PTGS2; 17-RELA; 18-STAT1; 19-TGFB1; 20-tp53.