Transcranial Ultrasound Stimulation of the Anterior Cingulate Cortex Reduces Neuropathic Pain in Mice

Figure 3

FUS stimulation promptly improved the mechanical withdraw threshold in the long-term experiment. Timeline of the long-term experiment (n = 12) (a). Ultrasound stimulation increased the mechanical withdraw threshold of the surgical side () (b). There were no significant changes in the mechanical withdraw threshold of the contralateral side. The bilateral thermal withdraw threshold, body weight, and sciatic nerve index between the FUS2 group and the Sham group (c–f). indicates statistical significance between the FUS2 group and the Sham group.

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