The Protective Effect of Ethyl Acetate and n-Butanol Fractions of Wine-Steamed Ligustri Lucidi Fructus on Diabetic Nephropathy in Rats

Table 2

The effect of WLL and its different polar fractions on 24 h urine protein of DN rats (mean ± SD, n = 10, mg/24 h).

Groups	Week 4	Week 8	Week 12
Normal	5.46 ± 0.39	5.02 ± 0.69	3.78 ± 0.69
Model	25.81 ± 2.84^##	33.77 ± 5.21^##	35.27 ± 3.32^##
WLL	7.52 ± 1.39	8.68 ± 1.21	7.28 ± 0.99
PE	24.04 ± 0.89	31.56 ± 1.75	34.21 ± 3.08
EtOAc	8.98 ± 1.31	11.03 ± 2.17	10.07 ± 0.99
n-BuOH	11.14 ± 2.57	12.69 ± 2.39	12.69 ± 1.41
Water	20.23 ± 3.09	27.76 ± 3.46	28.53 ± 1.93
Mef	10.26 ± 1.67	10.89 ± 1.19	10.69 ± 1.53

Significant differences with the normal group were designated as ^##P < 0.01; significant differences with the model group were designated as  < 0.01.