Multiple Risk Factors for Heart Disease: A Challenge to the Ethnopharmacological Use of Croton urucurana Baill.

Table 3

Body weight and relative heart and kidney weight in dyslipidemic and smoking rats that were treated with vehicle, Croton urucurana extract, and simvastatin + enalapril.

	Basal	C−	Croton urucurana (mg/kg)			SIM + ENAL
			30	100	300
Body weight (g)	166.3 ± 3.5	176.0 ± 1.1	174.0 ± 3.1	177.7 ± 2.5	174.9 ± 3.2	175.4 ± 1.9
Heart (%)	0.36 ± 0.02	0.48 ± 0.02^a	0.42 ± 0.01^b	0.39 ± 0.01^b	0.37 ± 0.01^b	0.37 ± 0.01^b
Kidney (%)	0.42 ± 0.01	0.49 ± 0.01^a	0.44 ± 0.01^b	0.42 ± 0.01^b	0.40 ± 0.01^b	0.46 ± 0.01

SIM + ENAL: simvastatin + enalapril. n = 8/group. The data are expressed as mean ± SEM. versus basal; versus C− (one-way ANOVA followed by Newman–Keuls post hoc test).