Yixintongmai Inhibits Proliferation and Migration and Promotes Apoptosis of Vascular Smooth Muscle Cells Cultured with High Glucose

Figure 5

Yixintongmai inhibits nuclear translocation of NF-κB and the expression of NF-κB of VSMCs cultured with high glucose. NG: normal glucose (5.5 mM); HG: high glucose (25 mM); HG + Y: high glucose (25 mM) and yixintongmai powder (360 μg/ml); the nuclear translocation of NF-κB in VSMCs under different conditions (a) and densitometry quantification of mean fluorescence intensity values shown by the ratio of integrated density and area of VSMCs under different conditions (b); Western blot of the expression of NF-κB p65 and phosphorylated NF-κB p65 (c), and densitometry quantification (d, e). Densitometry quantification values are shown by fold over NG or HG. Values are expressed as means ± SD of triplicate experiments. ; ; NS: not significant ().

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