Research Article
Proteomic Analysis and In Vivo Studies Reveal the Potential Gastroprotective Effects of CHCl3 and Aqueous Extracts of Ficus palmata
Table 2
Effect of Ficus palmata extracts: chloroform (Fp.CHCl3), aqueous (Fp.Aq), and atropine on charcoal meal transit time in rats.
| | Doses (mg/kg, p.o.) | Mean length of intestine (cm) | Distance moved by charcoal (cm) | % Intestinal transient | % Inhibition |
| | Saline (10 mL/kg) | 92.6 ± 1.6 | 90 ± 1.3 | 97.1 | - | | Fp.CHCl3 (50 mg/kg) | 79.8 ± 1.6 | 68 ± 1.7 | 85.21 | 12.24 | | Fp.CHCl3 (100 mg/kg) | 79.8 ± 1.6 | 66.2 ± 1.0 | 82.95 | 14.57 | | Fp.CHCl3 (300 mg/kg) | 78.8 ± 0.3 | 62 ± 2.0 | 78.68 | 18.97 | | Fp.Aq (50 mg/kg) | 79.8 ± 0.6 | 62 ± 0.9 | 77.69 | 19.98 | | Fp.Aq (100 mg/kg) | 77 ± 0.8 | 56 ± 0.8∗∗ | 72.72 | 25.10 | | Fp.Aq (300 mg/kg) | 47 ± 1.3 | 71.6 ± 0.5∗∗∗ | 65.64 | 32.39 | | Atropine (0.1 mg/kg, i.p.) | 90.8 ± 0.9 | 15.6 ± 0.6∗∗∗ | 17.18 | 82.31 |
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vs. control (saline) group, one-way ANOVA followed by post hoc Tukey’s test, n = 5. |
