Research Article

Ablation Therapy Combined with EGFR TKIs in the Treatment of Advanced Non-Small Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials

Table 1

General characteristics of included studies.

Physical ablation joint targetingTargeted or joint chemotherapyCombined with chemotherapyOutcome indicators
ExamplesMenWomenPhases III-IVExamplesMenWomenPhases III-IV

Guo et al., 20165538175555371855Yes, TP①②③④⑦
Fu et al., 20183424103434231134Yes, TP①②③④
Guo et al., 20174331124343291443Yes, TP①②③④
Yu et al., 20195526295555282755No①②③⑦
Xu et al., 201118018181801818No①②③⑤⑥
Zhang et al., 201532UnknownUnknown3232UnknownUnknown32TP, AP, or GP①②③④⑦
U.S., 201754UnknownUnknown5454UnknownUnknown54TP, AP, or GP①②③④⑦
Chen et al., 20154021194040202040Yes, TP1 ②③⑥⑦⑧
Zhang, 20164525204545242145Yes, TP①②③④

Outcome indicators: (1) full remission rate, (2) partial remission rate, (3) disease control rate, (4) quality of life, (5) 1-year survival rate, (6) no progression survival, (7) adverse reactions, and (8) OS.