Research Article
Ablation Therapy Combined with EGFR TKIs in the Treatment of Advanced Non-Small Cell Lung Cancer: A Meta-Analysis of Randomized Controlled Trials
Table 1
General characteristics of included studies.
| | Physical ablation joint targeting | Targeted or joint chemotherapy | Combined with chemotherapy | Outcome indicators | Examples | Men | Women | Phases III-IV | Examples | Men | Women | Phases III-IV |
| Guo et al., 2016 | 55 | 38 | 17 | 55 | 55 | 37 | 18 | 55 | Yes, TP | ①②③④⑦ | Fu et al., 2018 | 34 | 24 | 10 | 34 | 34 | 23 | 11 | 34 | Yes, TP | ①②③④ | Guo et al., 2017 | 43 | 31 | 12 | 43 | 43 | 29 | 14 | 43 | Yes, TP | ①②③④ | Yu et al., 2019 | 55 | 26 | 29 | 55 | 55 | 28 | 27 | 55 | No | ①②③⑦ | Xu et al., 2011 | 18 | 0 | 18 | 18 | 18 | 0 | 18 | 18 | No | ①②③⑤⑥ | Zhang et al., 2015 | 32 | Unknown | Unknown | 32 | 32 | Unknown | Unknown | 32 | TP, AP, or GP | ①②③④⑦ | U.S., 2017 | 54 | Unknown | Unknown | 54 | 54 | Unknown | Unknown | 54 | TP, AP, or GP | ①②③④⑦ | Chen et al., 2015 | 40 | 21 | 19 | 40 | 40 | 20 | 20 | 40 | Yes, TP | 1 ②③⑥⑦⑧ | Zhang, 2016 | 45 | 25 | 20 | 45 | 45 | 24 | 21 | 45 | Yes, TP | ①②③④ |
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Outcome indicators: (1) full remission rate, (2) partial remission rate, (3) disease control rate, (4) quality of life, (5) 1-year survival rate, (6) no progression survival, (7) adverse reactions, and (8) OS.
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