Tribulus terrestris L. Extract Protects against Lipopolysaccharide-Induced Inflammation in RAW 264.7 Macrophage and Zebrafish via Inhibition of Akt/MAPKs and NF-κB/iNOS-NO Signaling Pathways

Figure 1

The cytotoxicity of BJL and BJL-decreased LPS-induced NO release in RAW 264.7 cells. (a) RAW 264.7 cells were treated LPS (0.3 μg/ml) with or without various concentrations of BJL (3, 10, and 30 μg/ml) for 24 h and then followed by NO release assay. (b) RAW 264.7 cells were treated with various concentrations of BJL (3, 10, 30, 50, 80, and 100 μg/ml) for 24 h and the cell viability was measured by MTT assay. (c) RAW 264.7 cells were treated LPS (0.3 μg/ml) with or without various concentrations of BJL (3, 10, and 30 μg/ml) for 24 h and the cell viability was measured by MTT assay. Data were presented as the percentages of the control group. Results were means ± S.E.M. of more than 3 independent experiments. versus the control group. , , and versus the LPS-treated group.

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