Use of Network Pharmacology to Explore the Mechanism of Gegen (Puerariae lobatae Radix) in the Treatment of Type 2 Diabetes Mellitus Associated with Hyperlipidemia

Table 1

Active ingredients and ADME parameters of Gegen.

No.	MOL ID	Molecule name	OB (%)	DL
M1	MOL001999	Scoparone	74.75	0.09
M2	MOL000392	Formononetin	69.67	0.21
M3	MOL002959	3′-Methoxydaidzein	48.57	0.24
M4	MOL003629	Daidzein-4,7-diglucoside	47.27	0.67
M5	MOL000358	Beta-sitosterol	36.91	0.75
M6	MOL012297	Puerarin	24.03	0.69
M7	MOL000390	Daidzein	19.44	0.19
M8	MOL000481	Genistein	17.93	0.21
M9	MOL000663	Lignoceric acid	14.9	0.33
M10	MOL009720	Daidzin	14.32	0.73
M11	MOL000441	Lupenone	11.66	0.78
M12	MOL000391	Ononin	11.52	0.78

Notes: The compounds do not meet the inclusion criteria based on ADME (OB ≥ 30% and DL ≥ 0.18) but have been reported to have metabolic regulatory effects. Abbreviations: OB, oral bioavailability; DL, drug-likeness.