Platelet Distribution Width and Mortality in Hemodialysis Patients
Table 1
Baseline characteristics and laboratory parameters stratified by PDW.
Cohort, n = 496
PDW < 16.31%, n = 258
PDW ≥ 16.31%, n = 238
value
Age (years)
52.5 ± 16.6
53.0 ± 10.6
52.4 ± 17.0
0.773
Male, n (%)
293 (59.1%)
94 (36.4%)
199 (83.6%)
<0.001
CCI
4.39 ± 1.71
4.28 ± 1.69
4.50 ± 1.94
0.106
Dialysis vintage (months)
85.8 (71.2, 110.3)
85.0 (70.9, 110.3)
86.1 (65.1, 99.8)
0.364
Dry weight (kg)
60.4 ± 11.1
57.6 ± 11.9
60.6 ± 13.7
0.150
BMI (kg/m2)
23.6 ± 5.0
21.5 ± 4.2
24.5 ± 5.3
0.049
Kt/V
1.43 (1.26, 1.64)
1.48 (1.28, 1.66)
1.36 (1.27, 1.52)
0.362
Access thrombosis, n (%)
115 (23.2%)
62 (24.0%)
53 (22.3%)
0.762
Access, n (fistula/catheter)
480/16
252/6
228/10
0.641
Systolic (mmHg)
134 ± 21
134 ± 16
140 ± 22
0.543
Diastolic (mmHg)
80 ± 15
79 ± 13
83 ± 15
0.414
Creatinine (mg/dL)
8.2 (7.5, 9.8)
6.9 (4.1, 8.3)
9.0 (8.0, 10.8)
0.005
Albumin (g/L)
43.4 ± 4.3
42.9 ± 3.3
37.0 ± 5.8
0.003
Hs-CRP (ug/mL)
2.5 (0.7, 5.3)
2.0 (0.9, 4.1)
5.8 (1.4, 7.9)
<0.001
Hemoglobin (g/L)
107.1 ± 23.8
108.6 ± 19.2
102.2 ± 24.7
0.571
Platelet counts (x 10^9/L)
150 ± 73.0
152 ± 66.4
144.2 ± 76.4
0.066
MPV (fL)
9.3 ± 5.3
9.2 ± 3.2
10.0 ± 7.7
0.022
PDW, platelet distribution width; CCI, Charlson comorbidity index; BMI, body mass index; hs-CRP, high-sensitive C-reactive protein; MPV, mean platelet volume.