Research Article

Platelet Distribution Width and Mortality in Hemodialysis Patients

Table 1

Baseline characteristics and laboratory parameters stratified by PDW.

Cohort, n = 496PDW < 16.31%, n = 258PDW ≥ 16.31%, n = 238 value

Age (years)52.5 ± 16.653.0 ± 10.652.4 ± 17.00.773
Male, n (%)293 (59.1%)94 (36.4%)199 (83.6%)<0.001
CCI4.39 ± 1.714.28 ± 1.694.50 ± 1.940.106
Dialysis vintage (months)85.8 (71.2, 110.3)85.0 (70.9, 110.3)86.1 (65.1, 99.8)0.364
Dry weight (kg)60.4 ± 11.157.6 ± 11.960.6 ± 13.70.150
BMI (kg/m2)23.6 ± 5.021.5 ± 4.224.5 ± 5.30.049
Kt/V1.43 (1.26, 1.64)1.48 (1.28, 1.66)1.36 (1.27, 1.52)0.362
Access thrombosis, n (%)115 (23.2%)62 (24.0%)53 (22.3%)0.762
Access, n (fistula/catheter)480/16252/6228/100.641
Systolic (mmHg)134 ± 21134 ± 16140 ± 220.543
Diastolic (mmHg)80 ± 1579 ± 1383 ± 150.414
Creatinine (mg/dL)8.2 (7.5, 9.8)6.9 (4.1, 8.3)9.0 (8.0, 10.8)0.005
Albumin (g/L)43.4 ± 4.342.9 ± 3.337.0 ± 5.80.003
Hs-CRP (ug/mL)2.5 (0.7, 5.3)2.0 (0.9, 4.1)5.8 (1.4, 7.9)<0.001
Hemoglobin (g/L)107.1 ± 23.8108.6 ± 19.2102.2 ± 24.70.571
Platelet counts (x 10^9/L)150 ± 73.0152 ± 66.4144.2 ± 76.40.066
MPV (fL)9.3 ± 5.39.2 ± 3.210.0 ± 7.70.022

PDW, platelet distribution width; CCI, Charlson comorbidity index; BMI, body mass index; hs-CRP, high-sensitive C-reactive protein; MPV, mean platelet volume.