Platelet Distribution Width and Mortality in Hemodialysis Patients
Table 2
Association between PDW and all-cause and cardiovascular mortality using Cox regression models.
Model 1
Model 2
Model 3
HR (95% CI)
HR (95% CI)
HR (95%CI)
All-cause mortality
PDW < 16.31%
Reference
PDW ≥ 16.31%
1.53 (1.33–5.92)
0.001
1.50 (1.21–5.11)
0.003
1.49 (1.15–6.82)
0.007
Quartiles of PDW
Quartile 1
Reference
Quartile 2
1.21 (1.06–5.36)
0.037
1.19 (1.05–5.41)
0.0041
1.15 (1.04–5.84)
0.045
Quartile 3
1.42 (1.09–5.17)
0.021
1.38 (1.07–5.28)
0.024
1.31 (1.06–5.53)
0.029
Quartile 4
1.69 (1.18–4.85)
<0.001
1.64 (1.21–5.02)
<0.001
1.59 (1.18–5.30)
0.001
for trend
<0.001
<0.001
<0.001
CVD mortality
PDW < 16.31%
Reference
PDW ≥ 16.31%
2.51 (1.53–3.59)
0.002
2.46 (1.62–4.01)
0.008
2.26 (1.44–3.63)
0.011
Quartiles of PDW
Quartile 1
Reference
Quartile 2
2.02 (1.41–3.82)
0.003
1.96 (1.37–3.97)
0.006
1.87 (1.30–4.05)
0.012
Quartile 3
2.39 (1.43–3.53)
0.001
2.31 (1.40–3.61)
0.002
2.27 (1.34–3.79)
0.003
Quartile 4
2.94 (1.59–3.58)
<0.001
2.86 (1.53–3.67)
<0.001
2.71 (1.49–3.76)
<0.001
for trend
<0.001
<0.001
<0.001
Model 1: crude analysis. Model 2: adjustment for age, sex, and CCI. Model 3: adjustment for model 2 and BMI, creatinine, albumin, hs-CRP, and MPV. PDW, platelet distribution width; CCI, Charlson comorbidity index; BMI, body mass index; hs-CRP, high-sensitive C-reactive protein; MPV, mean platelet volume.
