Relaxant Effect of Urginea maritima on Tracheal Smooth Muscle Mediated by the Effect on Beta-2 Adrenergic, Muscarinic Receptors and Calcium and Potassium Channels

Table 1

Experiment groups. Trachea of incubated groups subjected to different channel blocker or antagonists in organ bath first followed by contraction of TSM by KCl or methacholine after 10 min.

Contractile agent	Condition	Incubating agent	Mechanisms	n
KCl (60 mM)	Nonincubated tissues	—	—	n = 8
	Incubated tissues	Atropine (1 μM)	Muscarinic receptor inhibition	n = 8
		Indomethacin (1 μM)	Cyclooxygenase inhibition	n = 8
		Chlorphenamine (1 μM)	Histamine (H1) receptor inhibition	n = 8
Methacholine (10 μM)	Nonincubated tissues	—	—	n = 8
	Incubated tissues	Diltiazem (5 μM)	Calcium channel blocking	n = 8
		Glibenclamide (1 μM)	Potassium channel opening	n = 8
		Propranolol (1 μM)	Β2-adrenoceptor stimulation	n = 8