Review Article
Meta-Analysis of Clinical Efficacy and Safety of Tripterygium wilfordii Polyglycosides Tablets in the Treatment of Chronic Kidney Disease
Table 3
Results of meta-analysis of 24-hour urinary protein.
| | Subgroup analysis | No. of studies | Weighted combination | Heterogeneity | Egger’s bias value | Metaregression
value | | WMD [95% conf. interval] | value | I2 | value |
| | Disease type | | NS | 25 | −0.690 (−0.829, −0.551) | | 94.2% | | | | | RNS | 12 | −0.500 (−0.629, −0.370) | | 77.7% | | | | PNS | 13 | −6.092 (−7.171, −5.014) | | 99.8% | | | | MN | 3 | −0.290 (−0.533, −0.048) | | 59.2% | | | | IgAN | 1 | −1.400 (−2.615, −0.185) | | — | — | — |
| | Mode of medication | | Single drug | 5 | −0.531 (−0.612, −0.451) | | 85% | | | | | Combined use of drugs | 49 | −0.501 (−0.525, −0.477) | | 99.1% | | |
| | Course of treatment | | <6 months | 17 | −0.531 (−0.563, −0.498) | | 99.7% | | | | | ≥6 months | 22 | −0.506 (−0.553, −0.459) | | 94.9% | | | | ≥12 months | 14 | −0.442 (−0.485, −0.399) | | 74.1% | | | | Not reported | 1 | −1.720 (−2.140, −1.300) | | — | — | — |
| | Age of the patient (year) | | 0–18 | 1 | −0.657 (−0.766, −0.547) | | — | — | — | | | 19–65 | 39 | −0.606 (−0.824, −0.388) | | 93.4% | | — | | >66 | 14 | −4.871 (−5.827, −3.915) | | 99.7% | | — | | Total | 54 | −0.503 (−0.526, −0.481) | | 99.0% | | | — |
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