Review Article
Meta-Analysis of Clinical Efficacy and Safety of Tripterygium wilfordii Polyglycosides Tablets in the Treatment of Chronic Kidney Disease
Table 4
Meta-analysis of reducing serum creatinine level in the experimental group and control group.
| | Subgroup analysis | No. of studies | Weighted combination | Heterogeneity | Egger’s bias
value | Metaregression
value | | WMD [95% conf. interval] | value | I2 | value |
| | Disease type | | NS | 15 | −11.764 (−14.967, −8.561) | | 96.2% | | | | | RNS | 6 | −6.479 (−8.960, −3.998) | | 11.5% | | | | PNS | 8 | −11.101 (−13.966, −8.235) | | 36.2% | | | | MN | 2 | 2.304 (−20.951, 25.558) | | 92.1% | | | | Mode of medication | | Single drug | 1 | −8.13 (−12.039, −7.233) | | 0.0% | | — | | | Combined use of drugs | 30 | −9.688 (−12.133, −7.243) | | 94.4% | | | | Course of treatment | | <6 months | 11 | −12.520 (−16.473, −8.566) | | 78.8% | | | | | ≥6 months | 14 | −6.177 (−8.431, −3.924) | | 90.1% | | | | ≥12 months | 6 | −3.029 (−9.316, 3.258) | | 76.4% | | | | Not reported | 1 | −66.320 (−76.691, −55.949) | | — | — | — | | Age of the patient (year) | | 19–65 | 21 | −9.049 (−11.740, −6.357) | | 94.7% | | | | | >66 | 10 | −11.120 (−13.762, −8.478) | | 46.6% | | | | Total | 31 | −9.636 (−12.039, −7.233) | | 94.3% | | | — |
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