Review Article

Meta-Analysis of Clinical Efficacy and Safety of Tripterygium wilfordii Polyglycosides Tablets in the Treatment of Chronic Kidney Disease

Table 5

Meta-analysis of reducing blood urea nitrogen level in the experimental group and control group.

Subgroup analysisNo. of studiesWeighted combinationHeterogeneityEgger’s bias
value
Metaregression
value
WMD [95% conf. interval] valueI2 value

Disease type
NS12−0.536 (−0.832, −0.241)69.1%0.416
RNS6−0.000 (−0.847, 0.846)97%0.252
PNS4−0.114 (−1.360, 1.132)95%0.061
MN2−0.555 (−1.204, 0.095)0.0%0.673
Mode of medication
Single drug1−0.93 (−1.536, 0.324)84.3%
Combined use of drugs23−0.298 (−0.644, 0.049)91.6%
Course of treatment
<6 months6−0.38 (−1.07, 0.31)93.2%
≥6 months14−0.235 (−0.693, 0.223)90.6%
≥12 months4−0.484 (−0.859, −0.108)27.3%
Age of the patient (year)
19–6517−0.325 (−0.722, 0.071)92.2%P < 0.05
>667−0.310 (−1.046, 0.426)89.9%
Total24−0.326 (−0.661, 0.009)91.3%