Review Article
Meta-Analysis of Clinical Efficacy and Safety of Tripterygium wilfordii Polyglycosides Tablets in the Treatment of Chronic Kidney Disease
Table 8
Meta-analysis of the incidence of gastrointestinal adverse reactions.
| | Subgroup analysis | No. of studies | Weighted combination | Heterogeneity | Egger’s bias
value | Metaregression
value | | OR [95% conf. interval] | value | I2 | value |
| | Disease type | | NS | 16 | 0.604 (0.391, 0.932) | | 0.0% | | | | | RNS | 4 | 0.890 (0.414, 1.913) | | 17.6% | | | | PNS | 8 | 0.686 (0.340, 1.383) | | 0.0% | | | | MN | 2 | 1.859 (0.493, 7.002) | | 0.0% | | |
| | Mode of medication | | Single drug | 3 | 0.737 (0.258, 2.105) | | 0.0% | 0.455 | | | | Combined use of drugs | 27 | 0.727 (0.523, 1.011) | | 0.0% | 0.73 | |
| | Course of treatment | | <6 months | 8 | 0.783 (0.428, 1.433) | | 61.4% | | | | | ≥6 months | 15 | 0.796 (0.520, 1.218) | | 51.4% | | | | ≥12 months | 7 | 0.501 (0.236, 1.063) | | 40.2% | | |
| | Age of the patient (year) | | 0–18 | 1 | 2.211 (0.484, 10.092) | | 91.0% | | — | | | 19–65 | 20 | 0.711 (0.482, 1.047) | | 47.7% | | | | >66 | 9 | 0.642 (0.356, 1.159) | | 24.7% | | | | Total | 30 | 0.711 (0.517, 0.980) | | 0.0% | | | — |
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