Quantitative and Molecular Similarity Analyses of the Metabolites of Cold- and Hot-Natured Chinese Herbs

Figure 4

Molecular structure similarity of the metabolites and the metabolite content ratio of cold-to hot-natured herbs. The hierarchical tree is constructed using the results of Tanimoto coefficients, and the similarity approach between the molecules of various metabolites is distance-based. The common structure of each classification is represented on the right side of the hierarchical tree. For easy comparison of the ratio of cold-to hot-natured herbs, the left vertical bar chart displays these ratios calculated from the average values of each metabolite. The red-colored bars indicate the high metabolite concentration in hot/warm-natured herbs, and the blue-colored bars indicate the high metabolite concentration in cold-natured herbs.