Evidence-Based Complementary and Alternative Medicine / 2021 / Article / Tab 5 / Research Article
An Apriori Algorithm-Based Association Rule Analysis to Identify Acupoint Combinations for Treating Diabetic Gastroparesis Table 5 Potential efficacy of the core acupoints for DGP treatment.
Point Chinese name English name Primary meridians Efficacy BL18 [49 ] Ganshu Liver locus Bladder Activation of CRH-like neurons; modulation of the expressions of CRH and GR in the PVN BL20 [54 ] Pishu Spleen locus Bladder Suppresses acid secretion and increases β -EP and SS BL23 [49 ] Shenshu Kidney locus Bladder Activation of CRH-like neurons; modulation of the expressions of CRH and GR in the PVN SP6 [50 –52 ] Sanyinjiao Crossroad at three Yin Spleen Protection of ICCs, amelioration of vascular endothelial dysfunction, and modulation of ghrelin PC6 [54 –56 ] Neiguan Inner pass Pericardium Suppresses acid secretion, increases β -EP and SS, modulates vagovagal neurocircuits, and decreases the number of double-labeled OT neurons and c-fos neurons
DGP: diabetic gastroparesis; CRH: corticotropin-releasing hormone; GR: glucocorticoid receptor; PVN: paraventricular nucleus of the hypothalamus; β -EP; beta-endorphin; SS: somatostatin; GD: gastric distention; ICCs: interstitial Cajal cells; OT: oxytocin.
